By Jennie R. Lill,Wendy Sandoval
The definitive advisor to the myriad analytical recommendations on hand to scientists interested in biotherapeutics research
Analytical Characterization of Biotherapeutics covers all present and rising analytical instruments and strategies used for the characterization of healing proteins and antigen reagents. From simple recombinant antigen and antibody characterization, to advanced analyses for more and more advanced molecular designs, the e-book explores the historical past of the research ideas and provides priceless insights into crucial rising analytical ideas. additionally, it frames serious questions warranting recognition within the layout and supply of a healing protein, exposes analytical demanding situations that can ensue whilst characterizing those molecules, and offers a couple of proven suggestions.
The first single-volume consultant of its sort, Analytical Characterization of Biotherapeutics brings jointly contributions from scientists on the innovative of biotherapeutics examine and production. Key themes coated in-depth comprise the structural characterization of recombinant proteins and antibodies, antibody de novo sequencing, characterization of antibody drug conjugates, characterization of bi-specific or different hybrid molecules, characterization of producing host-cell contaminant proteins, analytical instruments for biologics molecular overview, and more.
- Each bankruptcy is written via a well-known professional or specialists of their box who talk about present and leading edge methods to totally characterizing biotherapeutic proteins and antigen reagents
- Covers the entire diversity of characterization options for giant molecule dependent therapeutics
- Provides an up to date account of the most recent methods used for big molecule characterization
- Chapters hide the heritage had to comprehend the demanding situations handy, strategies to signify those huge molecules, and a precis of rising strategies for analytical characterization
Analytical Characterization of Biotherapeutics is an updated source for analytical scientists, biologists, and mass spectrometrists interested in the research of biomolecules, in addition to scientists hired within the prescribed drugs and biotechnology industries. Graduate scholars in biology and analytical technological know-how, and their teachers will locate it to be interesting and instructive supplementary reading.
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Additional info for Analytical Characterization of Biotherapeutics
Analytical Characterization of Biotherapeutics by Jennie R. Lill,Wendy Sandoval